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Time: 2026-01-07

Moxsy Borderlands 4 Tier List – Best Vault Hunter Builds Ranked for Endgame

Prepare for pure chaos and endless loot in Borderlands 4, where choosing your Vault Hunter is only the beginning. In this definitive Moxsy Borderlands 4 tier list, we break down every skill tree, ranking the strongest builds for late-game dominance. Whether you want devastating boss damage or unbreakable defense, this guide shows which Vault Hunter builds reign supreme.

Rafa – The Exo-Soldier

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  • S-Tier: Peacebreaker Cannons (Red Tree) Dominant and effortless. This setup summons autonomous shoulder turrets with insane damage and built-in lifesteal. Perfect for both mobbing and boss destruction, making it a staple of any top-tier Moxsy Borderlands 4 build.

    B-Tier: Apotheus Lance (Blue Tree) A solid shock-based setup that delivers heavy ranged damage. It performs well but relies on specific endgame gear for survivability in close-range duels.

    C-Tier: Arc Knives (Green Tree) Fun but flawed melee gameplay. Its weakness against flying or shielded enemies keeps it from serious late-game viability.

    Amon – The Forgeknight

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  • A-Tier: Crucible (Green Tree) A highly recommended pick in the Moxsy Borderlands 4 tier list. Combining Frost and Lightning, Amon’s Crucible tree unleashes devastating burst combos with his Frost Axe and Lightning Rod, freezing enemies before delivering a crit-heavy strike.

    B-Tier: Scourge (Blue Tree) A defensive, counterattack-focused style that rewards patience and gear optimization. Solid mid-game, but slow-starting for early playthroughs.

    C-Tier: Onslaught (Red Tree) A melee bruiser with remarkable durability, but slow boss-kill speed drags it down a tier.

    Vex – The Siren

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  • S-Tier: Incarnate (Green Tree) The ultimate boss-killer. Utilizing the Bloodletter skill, Vex applies unstoppable bleed effects that melt health bars. Combined with strong healing, it’s arguably the most overpowered option in Moxsy’s Borderlands 4 builds.

    A-Tier: Dead Ringer (Blue Tree) A summoner tree allowing players to send spectral allies into battle. Strong for leveling and crowd control, but fragile minions require positioning awareness.

    C-Tier: Phase Familiar (Red Tree) Centered on the AI pet “Trouble.” Unfortunately, poor AI responsiveness and scaling issues make this build underperform in tough encounters.

    Harlowe – The Gravitar

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  • S-Tier: Chroma Accelerator (Red Tree) A game-breaking power build that channels nuclear explosions into your gunfire for nearly infinite DPS. Demands solid cooldown management but rewards mastery with devastating results — a top entry in the Moxsy Borderlands 4 tier list.

    A-Tier: Flux Generator (Green Tree) An excellent hybrid between damage amplification and control. Generates energy fields that link enemies, ramping up your burst potential massively.

    B-Tier: Zero Point (Blue Tree) Superior crowd-control for mobbing, but too situational against bosses, reducing its overall ranking.

    Gear Up for Greatness

    While skill trees define your style, great loot defines your power. Borderlands 4 offers billions of guns, and finding the perfect one can be a grind. If you want to optimize fast, MMOMAX provides a safe selection of Borderlands 4 gear to help your chosen build shine.

    Choose your Vault Hunter wisely, follow this Moxsy Borderlands 4 tier list, and craft your path to becoming the ultimate endgame legend!